What is PureC®?
PureC® is a proven, palatable nutritional supplement that can be used for maintaining optimal health in dogs and cats, particularly under conditions such as stress, injury and illness. PureC® is pharmaceutical grade sodium ascorbate (a form of vitamin C). No fillers or any other substances have been added. The sodium ascorbate is 99.6% pure.
PureC® is a convenient and easy to use powder that you add to your pet's food. The powder is laboratory tested and of the highest quality (United States Pharmacopoeial specifications), providing you safety and peace of mind. It is a cost-effective, premium supplement which assists in keeping your dog and/or cat healthy.
Vitamin C - a powerful antioxidant
The most important function of vitamin C is its action as a powerful antioxidant, by which means it is able to protect your pet’s organs and tissues from damage by reactive oxygen species in the body. In particular, the antioxidant activity of vitamin C can have a protective effect against the development of joint disease and it protects muscle from damage by free radicals following strenuous exercise.
Vitamin C represents the major water-soluble antioxidant in plasma and tissues. Due to its water solubility, it can exist both within the cell (intracellular) and outside the cell (extracellular) and it is the most important antioxidant in extracellular fluids.
Vitamin C - vital for collagen synthesis
Vitamin C plays a vital role in collagen synthesis. Collagen is the main structural protein of connective tissues which support, connect, or separate different types of tissues and organs in the body. Thus, vitamin C is important for the structural integrity of every tissue and organ in the body. Deficiencies of vitamin C are manifest as connective tissue lesions (e.g. capillary fragility, periodontal disease, muscular weakness).
Tissues with high collagen contents include cartilage, tendons, ligaments, skin, corneas, bones (collagen being the main component of the organic part of bone), blood vessels, the gut, the dentin in teeth and intervertebral discs. Muscle also has a substantial collagen content. Vitamin C is therefore vital for the health of these tissues.
Because of its importance in the synthesis of collagen, vitamin C also plays a role in wound-healing and in angiogenesis (the process of new blood vessel formation).
Other functions of vitamin C
Vitamin C also plays an important role in maintaining normal immune function, thus protecting animals from infections. Additionally, it plays a role as an enzyme cofactor (a chemical required for an enzyme to work) and in metal ion metabolism. Further, it reduces the absorption of toxic metals such as lead, cadmium and vanadium.
The enzymes for which vitamin C is a cofactor are involved in various important metabolic reactions in the body:
- the biosynthesis of carnitine, a compound required for the transport of fatty acids
- the biosynthesis of some hormones, including norepinephrine (a hormone and neurotransmitter) and some peptide hormones
- the metabolism of the amino acids, tyrosine and tryptophan
- the metabolism of xenobiotics (foreign chemicals not normally naturally produced in the body), for example, drug metabolism/detoxification
- the synthesis of bile acids
It is also suspected to be involved in the process of steroidogenesis (the synthesis of steroids) in the adrenal gland.
Synthesis of vitamin C by animal species
Unlike humans (and guinea pigs), other animals such as dogs and cats, can synthesise (produce) vitamin C in their livers from glucose. Thus, healthy dogs and cats do not normally suffer from vitamin C deficiency or need supplements to prevent vitamin C deficiency. However, to produce adequate vitamin C, they need a properly functioning liver and adequate glucose.
Further, it is important to recognise that there may also be a difference between the minimal quantity of a vitamin required for prevention of deficiency symptoms and the optimum quantity required for achieving best performance (e.g. health and physical performance in performance animals). Supply of vitamins somewhere between minimum and optimum level may occur frequently in practice, resulting in nonspecific depression of health or performance. Further, in virtually all forms of stress, vitamin C is used rapidly and tissue levels are decreased. Even in dogs and cats, there are conditions when more vitamin C may be required than the body can produce.
Conditions when vitamin C supplementation may be beneficial
Conditions when vitamin C supplementation may be beneficial include:
• intense exercise (e.g. racing greyhounds)
• high production (such as lactating females and rapid growth in young animals)
• environmental stress (cold or elevated temperatures, and pollutants)
• mental stress (separation stress, stress of a new environment, weaning, transportation, competitions, and unusual or excessive handling)
• illness, including both acute and chronic infections
• diseases (particularly arthritis)
• metabolic disorders
• genetic problems like canine hip dysplasia (CHD) in dogs
• aged animals (as animals age they are less able to produce sufficient vitamin C, generally because of decreased liver function)
• immune function depression
• nutritionally unbalanced diets (including insufficient vitamins E and A, β-carotene, energy, protein, selenium, iron, etc)
An economical way to supplement your pet's diet with vitamin C
Supplementation with PureC® is an economical way to enhance your pet's diet with the benefits of vitamin C. Vitamin C in powder supplements is more stable than in other presentations. In particular, it can be lost upon heating (for example, when feeds or supplements are pelleted). Further, when vitamin C is added to animal feeds, this is mainly in very small amounts.
How safe is vitamin C?
Vitamin C is of low toxicity and high intakes are normally well tolerated. Oral vitamin C may be administered to most animal species at doses of several grams per kilogram of body weight without any obvious side effects. There have been occasional reports of diarrhoea at high doses.
As vitamin C is water soluble, ingested amounts that are surplus to requirements are readily excreted in urine, rather than accumulating in the body.